It's not a simple as just work and life. There are many external factors that have to be considered, but one thing I strongly believe in is working for a company that has a culture that values the life side of every employee. European companies have tended to do a better job at this than their US counterparts. When European's take vacation they unplug and take a real vacation. I think this is good not only for the employee but for the company as well. You have to be able to effectively cover for those while they are on vacation and appreciate times when they are away.
There's a good overview article HERE.